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MEMBER ACCESS: Mercury Depletes Glutathione Peroxidase-Toxic Mechanisms In Alzheimer’s Disease Risk

The research demonstrating the deleterious and toxic effects of mercury on brain function and structure in neurodegenerative disease processes is plentiful. Adding to the research literature, a May/2009 study demonstrated that methylmercury* induces neurotoxicity, by significantly inactivating one the brain's primary antioxidant defense buffers, glutathione peroxidase (GPx). (1) ...
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Image courtesy of the National Institute on Aging/National Institutes of Health

Member Access: Oxidative Stress and the Thromboxane Receptor–A Central Pivot in the Production of Neurofibrillary Tangles and Amyloid-beta

New research published Oct. 13 by the journal Neurobiology of Aging revealed that the free radicals produced during oxidative stress bind to a protein receptor in the brain designated as “the Thromboxane Receptor A2 (TP)”. The study, “Modulation of AD Neuropathology and Memory Impairments by the Isoprostane F2α Is Mediated ...
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Member Access: TREM2 gene mutation raises the risk of Alzheimer’s disease

By Ralph Sanchez, MTCM, CNS, D.Hom. Recently (11/13), a rare variant of the TREM2 gene, designated as R47H, was shown to increase the risk of developing Alzheimer’s disease. Individuals with the variant may be up to 3 to 5 times more likely to develop late-onset Alzheimer’s disease (LOAD). This susceptibility ...
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MEMBER ACCESS: Blueberry Polyphenols Protect the Brain from the Degenerative Processes Associated with Brain Aging and Alzheimer’s Disease

The study of plant and fruit polyphenols, a rich source of dietary antioxidants, represents one of the most promising areas of research in the field of anti-aging, and the prevention of degenerative disorders such as Alzheimer's disease. Recent and ongoing research indicates that polyphenols present in berries and other fruits ...
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MEMBER ACCESS: Brain-Derived Neurotrophic Factor – Growth Factor Demonstrates Promise in the Protection Against Alzheimer’s Disease Progression

By Ralph Sanchez, L.Ac.CNS,D.Hom. One of the longest held thoughts about damage to our brain's cells (neurons) was that once they were lost, it was a fait accompli. Damaged neurons were considered damaged goods, never to regain their function, and without any hope for regeneration. Fortunately, for those concerned about ...
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MEMBER ACCESS: Mild Cognitive Impairment (MCI)–Telltale Signs That You May Be At Increased Risk for Dementia or Alzheimer’s Disease

By Ralph Sanchez, L.Ac.,CNS,D.Hom Long before a diagnosis of Dementia or Alzheimers disease (AD) is given, brain damage is occurring that leads to, and reflects the gradual downward spiral of mental decline that typifies AD. A cluster of signs that define Mild Cognitive Impairment (MCI), especially memory loss and forgetfulness, ...
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The Alzheimer's Solution

mailchi.mp/caaa8f6a5148/from-braindefend-neurotoxins-to-be-aware-of A host of environmental toxins pose a significant health risk to the integrity of your brain (neurotoxins). Environmental neurotoxins are ubiquitous and your exposures to many of them may be passing under your radar.

The dangers of neurotoxic metals like mercury and lead are well known, yet the chronic exposure to a host of other toxic metals, pesticides, and chemicals generally are not so well recognized. In fact, a chemical toxin may be lurking in your take out container and....
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Testing for your risk of dementia and Alzheimer's disease - mailchi.mp/aa5b6f000e15/testing-for-your-risk-of-dementia-and-alzheimers-disease

An article from the University of Southern California that I link to in this BrainDefend™ newsletter, reports on research that is centered on an artificial intelligence analysis on an algorithm of blood-based biomarkers that can serve as a clinical screening tool in the risk assessment for late-onset Alzheimer's disease.

However, no need to wait for the study results as risk assessments for Alzheimer's are available now.
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What a tremendous resource! Thank you for putting all of this great research in one place! I am also extremely interested in warding off a family history of Alzheimer’s and Dementia. Medicine can be so very powerful when we are able to identify the biochemical inefficiencies, apply specific dietary and nutritional remedies and compile a protocol to heal not just an individual, but generations. Thank you Ralph!

Tim Walsh LAc

This is an incredible article! Very powerful information! Thank you so much for putting it together the way that you have. This information needs to get out to the masses. You explained that very well.

Dr. Jones

Absolutely the BEST article I have read on the insulin/AD connection. As always, your brilliance is very much appreciated!

Kristin Rotblatt, L.Ac.

Thank you so much for this well written article. Looking forward to future updates. Thanks for this well illustrated, researched, and detailed yet succinct article.

Dr. Shah Roath


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